InSilico Consulting
InSilico Consulting
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    • Home
    • Why Us?
      • Why Choose Us
      • Meet the Team
      • Portfolio
      • Collaborations
    • Services
      • Bioinformatics
      • Data Science
      • Quality Assurance
      • Website Design
    • Contact Us
    • Latest News
  • Home
  • Why Us?
    • Why Choose Us
    • Meet the Team
    • Portfolio
    • Collaborations
  • Services
    • Bioinformatics
    • Data Science
    • Quality Assurance
    • Website Design
  • Contact Us
  • Latest News

Bioinformatics

Leveraging over a decade of expertise to drive scientific discovery and innovation, our comprehensive suite of bioinformatics services is designed to support researchers in extracting meaningful insights from complex biological data.

Experimental Design

Effective experimental design is crucial for maximizing the potential of your bioinformatics research. 

We provide meticulous planning to ensure your experiments are structured to yield the most significant results. From grant proposals to power calculations, our expert guidance helps you optimise your experimental setup. 

We focus on understanding your research goals and aligning our strategies to achieve them, ensuring that every step of your sequencing experiments is thoughtfully planned and executed.

Ready to Chat?

Ready to take your business to the next level? Contact us today to schedule a consultation with one of our experts.

Get in Touch

DNA Sequencing

Innovative Consulting Services for Your Business

The field of DNA sequencing offers unparalleled opportunities to explore genetic data. 

Our team harnesses the latest advancements in bioinformatics to provide high-resolution genetic snapshots of organisms. By exploiting both new and existing genetic data, we uncover novel insights that drive your research forward. 


Our services in DNA sequencing include: 


  • 16s Ribosomal Sequencing: Identify and classify microorganisms with precision.
  • Polymorphism Detection: Discover genetic variations that impact traits and diseases.
  • Genome Assembly: Construct complete genome sequences from fragmented data.
  • Genome Annotation: Assign functional information to genomic elements.
  • BLAST Analysis: Compare your sequences against a comprehensive database.
  • Transposon Element Analysis: Investigate mobile genetic elements within genomes.
  • Source Analysis of Metagenome Findings: Determine the origins and functions of metagenomic data.

16s Ribosomal Sequencing

16s Ribosomal Sequencing

16s Ribosomal Sequencing

Identify and classify microorganisms with precision.

Polymorphism Detection

16s Ribosomal Sequencing

16s Ribosomal Sequencing

Discover genetic variations that impact traits and diseases.

Genome Assembly

16s Ribosomal Sequencing

Genome Annotation

Construct complete genome sequences from fragmented data.

Genome Annotation

Source Analysis of Metagenome Findings

Genome Annotation

Assign functional information to genomic elements.

Source Analysis of Metagenome Findings

Source Analysis of Metagenome Findings

Source Analysis of Metagenome Findings

 Determine the origins and functions of metagenomic data.

Transposon Element Analysis

Source Analysis of Metagenome Findings

Source Analysis of Metagenome Findings

Investigate mobile genetic elements within genomes.

RNA Sequencing

RNA sequencing (RNAseq) is a powerful tool for understanding gene expression and regulation. 


Our team has conducted hundreds of RNAseq analyses across various applications, helping researchers reveal how samples dynamically respond to treatments. 


Our RNA sequencing services include: 

Differential Gene Expression

Alternative Splicing Analysis

Alternative Splicing Analysis

Identify genes with significant changes in expression levels.

Alternative Splicing Analysis

Alternative Splicing Analysis

Alternative Splicing Analysis

Explore variations in RNA splicing patterns.

Pipeline Building

Alternative Splicing Analysis

Transcript Annotation

Develop customised RNAseq data analysis workflows.

Transcript Annotation

Alternative Splicing Analysis

Transcript Annotation

Characterise and annotate RNA transcripts.

Visualisation

Interpreting next-generation sequencing data can be challenging due to its complexity.

At InSilico Consulting, we specialise in advanced data visualisation techniques to make your data comprehensible and actionable. Whether you have specific graphical strategies in mind or are open to exploring new methods, we provide solutions tailored to your needs. 


Our visualisation services include: 


  • GNUPlot: Create high-quality plots and graphs.
  • RStudio: Utilise advanced statistical tools for data analysis.
  • Gene Ontology: Visualise functional categories of genes.
  • Gene Set Enrichment Analysis: Identify significantly enriched gene sets.
  • Clustering Analysis: Group similar data points to identify patterns.
  • Pathway Analysis: Map interactions and pathways within your data.

Sequencing Services

InSilico Consulting is proud to collaborate with the Bristol Genomics Facility at the University of Bristol. Together, we offer state-of-the-art genomics and transcriptomics services. 

Experts Jane Coghill and Christy Waterfall bring a wealth of experience in next-generation sequencing techniques, providing a range of sequencing options to support your research.

Find Out More

Commonly Used Software

Python
BASH
R
Git

Everything Else

We understand that research is often bespoke and unique. 

Our team thrives on the challenges of novel and custom projects. If you have specific bioinformatics needs or are exploring unconventional pipelines, we are here to help. 


Get in touch with us to discuss how we can support your research endeavours.


Get in Touch

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